{"id":13264,"date":"2018-11-28T08:48:09","date_gmt":"2018-11-28T05:48:09","guid":{"rendered":"https:\/\/www.cpapmerkezi.com\/?p=13264"},"modified":"2018-11-28T08:48:09","modified_gmt":"2018-11-28T05:48:09","slug":"uyku-apnesi-kolesterolu-artirir-mi","status":"publish","type":"post","link":"https:\/\/www.cpapmerkezi.com\/blog\/uyku-apnesi-kolesterolu-artirir-mi.html","title":{"rendered":"Uyku Apnesi Kolesterol\u00fc Art\u0131r\u0131r M\u0131?"},"content":{"rendered":"

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A\u011fustos ay\u0131nda Avrupa yay\u0131nlanan \u00e7al\u0131\u015fman\u0131n sonu\u00e7lar\u0131na g\u00f6re, Obstr\u00fcktif Uyku Apnesi (OSA) ile y\u00fcksek kolesterol d\u00fczeyleri aras\u0131ndaki ili\u015fkiyi g\u00f6sterdi. Her ikisi de ba\u011f\u0131ms\u0131z olarak daha y\u00fcksek kalp hastal\u0131\u011f\u0131 ve fel\u00e7 riski ile ili\u015fkilidir.<\/span><\/p>\n

Ara\u015ft\u0131rmada, daha \u00f6nce hiperlipidemi te\u015fhisi konmam\u0131\u015f ve lipid d\u00fc\u015f\u00fcr\u00fcc\u00fc ila\u00e7lar (statinler) re\u00e7ete edilmemi\u015f olan Avrupa’da yakla\u015f\u0131k 6.000 yeti\u015fkin yer alm\u0131\u015ft\u0131r. Ara\u015ft\u0131rmac\u0131lar OSA \u015fiddeti ile daha y\u00fcksek total kolesterol d\u00fczeyleri aras\u0131nda g\u00fc\u00e7l\u00fc bir ili\u015fki oldu\u011funu bildirmi\u015flerdir.<\/span><\/p>\n

Spesifik olarak, y\u00fcksek trigliserit konsantrasyonu, y\u00fcksek LDL-kolesterol (yayg\u0131n olarak \u201ck\u00f6t\u00fc\u201d kolesterol olarak bilinir) ve d\u00fc\u015f\u00fck LDL-kolesterol (bazen \u201ciyi\u201d kolesterol olarak tarif edilir), Uyku Apnesi ile ili\u015fkili uyku problemleriyle \u00f6rt\u00fc\u015f\u00fcyor.<\/span><\/p>\n

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OSA \u015fiddetinin \u00f6l\u00e7\u00fcmleri,\u00a0 Apne-Hipopnoea \u0130ndeksi (AHI), Oksijen Desat\u00fcrasyon \u0130ndeksi (ODI) ve ortalama, en d\u00fc\u015f\u00fck oksijen doygunlu\u011fu kullan\u0131larak yap\u0131ld\u0131.<\/span><\/p>\n

Bununla birlikte, ilgin\u00e7 olarak \u00e7al\u0131\u015fma ayn\u0131 zamanda bir co\u011frafi fakt\u00f6r de tan\u0131mlam\u0131\u015ft\u0131r. En y\u00fcksek lipit konsantrasyonlar\u0131, do\u011frulanm\u0131\u015f sonu\u00e7lara g\u00f6re Kuzey Avrupa’dan kat\u0131l\u0131mc\u0131lara kaydedildi.<\/span><\/p>\n

\u00d6nceki \u00e7al\u0131\u015fmalarda ayr\u0131ca, ya\u015f ve kilo baz\u0131nda OSA ile lipid d\u00fczeylerinin korelasyonunda istatistiksel olarak anlaml\u0131 farkl\u0131l\u0131klar oldu\u011fu g\u00f6sterilmi\u015ftir. A\u015f\u0131r\u0131 kilolu ve obezite, Uyku Apnesi potansiyelini art\u0131rma e\u011filimindedir ve bir\u00e7ok obez hasta, y\u00fcksek kan bas\u0131nc\u0131, y\u00fcksek kan \u015fekeri seviyesi ve y\u00fcksek kolesterol de dahil olmak \u00fczere anormal lipit seviyeleri de dahil olmak \u00fczere anormal metabolik sonu\u00e7lara sahiptir.<\/span><\/p>\n

2016 y\u0131l\u0131nda , Helsinki \u00dcniversitesi’nde yap\u0131lan bir ara\u015ft\u0131rmada , \u201ckolesterol ta\u015f\u0131nmas\u0131ndan sorumlu genler, iyi ve kaliteli bir uyku elde edecek birilerinin oldu\u011fu gibi uyku yoksunlu\u011fundan muzdarip olan biri kadar aktif de\u011fildir.\u201d<\/span><\/p>\n

Uyku yoksunlu\u011fu, bir\u00e7ok t\u0131bbi sorunla ili\u015fkilidir. Kaliteli uyku eksikli\u011fi v\u00fccudun ba\u011f\u0131\u015f\u0131kl\u0131k sistemini olumsuz y\u00f6nde etkiler, metabolik i\u015flevi bozar, iltihaplanmaya neden olabilir ve \u00e7o\u011fu zaman i\u015ftah\u0131 bozar.<\/span><\/p>\n

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Y\u00fcksek Kolesterol Nedir?<\/strong><\/span><\/h2>\n

Y\u00fcksek kolesterol, y\u00fcksek kalp hastal\u0131\u011f\u0131 ve fel\u00e7 riski ile ili\u015fkilidir. Kolesterol, proteinlere ba\u011flanan ve kan dola\u015f\u0131m\u0131 yoluyla v\u00fccut boyunca ta\u015f\u0131nan yararl\u0131 bir ya\u011f maddesidir.<\/span><\/p>\n

Bununla birlikte, \u00e7ok iyi bir \u015fey arter t\u0131kan\u0131kl\u0131\u011f\u0131na yol a\u00e7abilir. Total kolesterol, v\u00fccutta bulunan en yayg\u0131n ya\u011f t\u00fcr\u00fc olan d\u00fc\u015f\u00fck dansiteli lipoprotein (LDL), y\u00fcksek dansiteli lipoprotein (HDL) ve trigliserit konsantrasyonu ile \u00f6l\u00e7\u00fcl\u00fcr.<\/span><\/p>\n

Yayg\u0131n bilgelik, kolesterol ve kalp hastal\u0131\u011f\u0131 aras\u0131nda bir ba\u011flant\u0131ya i\u015faret ederken, kan\u0131tlar ortaya \u00e7\u0131kan kan\u0131tlara g\u00f6re daha karma\u015f\u0131kt\u0131r. Ve hala y\u00fcksek kolesterol\u00fcn birincil neden mi yoksa sadece katk\u0131da bulunan bir fakt\u00f6r olup olmad\u0131\u011f\u0131 konusunda bir anla\u015fmazl\u0131k var. Bununla birlikte, bu son Uyku Apne hastalar\u0131 \u00e7al\u0131\u015fmalar\u0131, OSA ile anormal kolesterol aras\u0131ndaki ba\u011flant\u0131y\u0131 do\u011frulamaktad\u0131r.<\/span><\/p>\n

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Y\u00fcksek Kolesterol\u00fcn Belirtileri ve Olas\u0131 Sebepleri Nelerdir?<\/span><\/strong><\/h2>\n

Kan testi d\u0131\u015f\u0131nda kolesterol seviyelerini belirlemenin bir yolu yoktur ve anormal kolesterol d\u00fczeyleri ile ili\u015fkili ger\u00e7ek semptomlar yoktur. \u00c7o\u011fu t\u0131p uzman\u0131, kolesterol seviyelerinin yeti\u015fkinler i\u00e7in genellikle 200’den az olan sa\u011fl\u0131kl\u0131 aral\u0131kta kalmas\u0131n\u0131 sa\u011flamak i\u00e7in rutin kan testlerini \u00f6nermektedir.<\/span><\/p>\n

Genetik, kolesterol seviyelerini etkileyebilir, ancak sa\u011fl\u0131kl\u0131 bir diyet, rutin egzersiz ve sa\u011fl\u0131kl\u0131 bir kilonun korunmas\u0131, genellikle y\u00fcksek kolesterol e\u011filimine kar\u015f\u0131 koyabilir.<\/span><\/p>\n

Doktorlar genellikle kolesterol\u00fc kontrol etmek i\u00e7in ila\u00e7lardan ziyade ya\u015fam tarz\u0131 de\u011fi\u015fiklikleri re\u00e7ete ederler, ancak statinler ek bir koruma olarak yayg\u0131n olarak re\u00e7ete edilen bir ilac\u0131 temsil eder; Karaci\u011ferin \u00fcretti\u011fi kolesterol miktar\u0131n\u0131 d\u00fc\u015f\u00fcrerek ve ayn\u0131 zamanda kan dola\u015f\u0131m\u0131nda halihaz\u0131rda dola\u015fan a\u015f\u0131r\u0131 kolesterol\u00fcn giderilmesini kolayla\u015ft\u0131rarak \u00e7al\u0131\u015f\u0131rlar.<\/span><\/p>\n

\u0130la\u00e7lar\u0131n etkinli\u011fini ve statinlerin olas\u0131 ek faydalar\u0131n\u0131 de\u011ferlendirmek i\u00e7in devam eden \u00e7al\u0131\u015fmalar y\u00fcr\u00fct\u00fclmektedir. B\u00f6yle bir \u00e7al\u0131\u015fma, statin ila\u00e7lar\u0131n\u0131n uyku apnesinin kan damarlar\u0131na verdi\u011fi zarar\u0131 s\u0131n\u0131rland\u0131rabilece\u011fini g\u00f6stermektedir. “<\/span><\/p>\n

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Uyku Apnesi Kolesterol\u00fc Art\u0131r\u0131r m\u0131?<\/span><\/strong><\/h2>\n

Uyku Apnesi ve sa\u011fl\u0131ks\u0131z kolesterol birikimi aras\u0131ndaki korelasyon birka\u00e7 farkl\u0131 \u015fekilde ara\u015ft\u0131r\u0131lm\u0131\u015ft\u0131r. \u0130li\u015fkinin artan kan\u0131t\u0131 var. Ancak, nedensel etkinin hen\u00fcz bir g\u00f6stergesi yoktur. Di\u011fer bir deyi\u015fle, Uyku Apnesi hastal\u0131\u011f\u0131ndan muzdarip olanlar da y\u00fcksek kolesterole sahip olabilirler, ancak birinin di\u011ferine neden olabilece\u011fini d\u00fc\u015f\u00fcnmek i\u00e7in bir sebep yoktur.<\/span><\/p>\n

Aksine, hem Uyku Apnesi hem de anormal kolesterol d\u00fczeyleri di\u011fer sa\u011fl\u0131k sorunlar\u0131 i\u00e7in ba\u011f\u0131ms\u0131z risk fakt\u00f6rleri olarak d\u00fc\u015f\u00fcn\u00fclebilir.<\/span><\/p>\n

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    A\u011fustos ay\u0131nda Avrupa yay\u0131nlanan \u00e7al\u0131\u015fman\u0131n sonu\u00e7lar\u0131na g\u00f6re, Obstr\u00fcktif Uyku Apnesi (OSA) ile y\u00fcksek kolesterol d\u00fczeyleri aras\u0131ndaki ili\u015fkiyi g\u00f6sterdi. Her ikisi de ba\u011f\u0131ms\u0131z olarak daha y\u00fcksek kalp hastal\u0131\u011f\u0131 ve fel\u00e7 riski ile ili\u015fkilidir.<\/p>\n","protected":false},"author":1,"featured_media":13266,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_relevanssi_hide_post":"","_relevanssi_pin_for_all":"","_relevanssi_pin_keywords":"","_relevanssi_unpin_keywords":"","_relevanssi_related_keywords":"","_relevanssi_related_include_ids":"","_relevanssi_related_exclude_ids":"","_relevanssi_related_no_append":"","_relevanssi_related_not_related":"","_relevanssi_related_posts":"","_relevanssi_noindex_reason":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1821],"tags":[1880,2049,2168,2169,2170,2171,1954,1967,1834,1883,1884,1878,2172],"class_list":["post-13264","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uyku-apnesi","tag-apne","tag-felc","tag-hdl","tag-kalp-hastaligi","tag-kolesterol","tag-ldl","tag-nefes-durmasi","tag-osa","tag-osas","tag-uyku","tag-uyku-apne","tag-uyku-apnesi","tag-yuksek-kolesterol"],"aioseo_notices":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.cpapmerkezi.com\/blog\/wp-json\/wp\/v2\/posts\/13264","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cpapmerkezi.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.cpapmerkezi.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.cpapmerkezi.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cpapmerkezi.com\/blog\/wp-json\/wp\/v2\/comments?post=13264"}],"version-history":[{"count":0,"href":"https:\/\/www.cpapmerkezi.com\/blog\/wp-json\/wp\/v2\/posts\/13264\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.cpapmerkezi.com\/blog\/wp-json\/"}],"wp:attachment":[{"href":"https:\/\/www.cpapmerkezi.com\/blog\/wp-json\/wp\/v2\/media?parent=13264"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.cpapmerkezi.com\/blog\/wp-json\/wp\/v2\/categories?post=13264"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.cpapmerkezi.com\/blog\/wp-json\/wp\/v2\/tags?post=13264"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}